Colloque Inaugural du Consortium Myoparis
6 Décembre 2021, 9h-13h
Amphithéâtre Turing, bâtiment Sophie Germain (Campus des Grands Moulins, 8 place Aurélie Nemours, 75013 Paris).
PROGRAMME
9h-9:15h Welcome and introduction
Ana Ferreiro, ‘Basic and Translational Myology’ lab, UMR8251 BFA Université de Paris/CNRS & Reference Center for Neuromuscular Disorders, Neuromyology Depatment, Institut of Myology, Pitié-Salpêtrière Hospital.
Session 1 : Innovative models for studying muscle mechanics and thermodynamics.
9:15-9:30h Magnetic muscular multicellular aggregates: focusing on fluid-like properties of tissue models and driving macroscopic organization. Irène Nagle, Florence Delort, Sylvie Hénon, Sabrina Batonnet-Pichon, Claire Wilhelm, Myriam Reffay. Matière et Systèmes Complexes, UMR 7057, CNRS and University of Paris & Biologie Fonctionnelle et Adaptative, UMR 8251, CNRS and University of Paris
9:30-9:45h Thermodynamic description of muscle power production in living systems. Christophe Goupil, Eric Herbert, Thibault Chassereau. LIED-DyCo Université de Paris.
Session 2 : Genetic regulation of skeletal and cardiac muscle development and regeneration.
9:45-10h Role of LRRFIP2 in hypoxia regulation during heart development. Laura Ben Driss, Athanassia Sotiropoulos, Pascal Maire. Inserm U1016, Institut Cochin & CNRS UMR8104 & Université de Paris, Paris, France
10-10:15h Role of Srf in the control of myoblast fusion. Kassandra Kobon, Voahangy Randrianarison-Huetz, Sandra Sara, Pascal Maire, and Athanassia Sotiropoulos. Inserm U1016, Institut Cochin & CNRS UMR8104 & Université de Paris, Paris, France
10:15-10:30h The Role of LRRFIP2 in Muscle Stem Cells During Adult Skeletal Muscle Regeneration. Rouba Madani, Athanassia Sotiropoulos, Pascal Maire. Inserm U1016, Institut Cochin & CNRS UMR8104 & Université de Paris, Paris, France.
10:30-10:45h General discussion
10:45-11:15h Coffee break and informal discussions
Session 3 : Novel epigenetic, transcriptional and post-transcriptional mechanisms in muscle physiology and disease.
11:15-11:30h SETDB1 regulates the TGFβ-induced fibrosis in Duchenne muscular dystrophy muscles: effect on the secretome?. Alice Granados, Maeva Zamperoni, Laurence Delmaestro, Costas Bouyioukos, Sonia Albini and Slimane Ait-Si-Ali Université de Paris, CNRS, Epigenetics and Cell Fate, UMR7216, F-75013 Paris
11:30-11:45h Small nucleolar RNAs SNORA40 play a role in muscle differentiation. Baptiste Bogard, Claire Francastel and Florent Hubé. Université de Paris, CNRS, Epigenetics and Cell Fate, UMR7216, F-75013 Paris
11:45-12h The ASC-1 complex, an emerging critical node in muscle and motoneuron development and disease.
Justine Meunier, Andrew Ho, Rocío Nur Villar-Quiles, Bertrand Cosson, Ana Ferreiro, Isabelle Duband-Goulet.
‘Basic and Translational Myology’ lab, UMR8251 BFA Université de Paris/CNRS & Université de Paris, CNRS, Epigenetics and Cell Fate, UMR7216, F-75013 Paris
12-12:15h General discussion
Session 4 : Translational and therapeutic developements.
12:15-12:30h Identification of the mode of action of flunarizine in neuroprotection. Badih Salman, Steve Cottin, Perrine Delers, Delphine Sapaly, Suzie Lefebvre. Université de Paris, Faculté des Sciences Fondamentales et Biomédicales, T3S, UMR 1124 INSERM, 75006 Paris, France.
12:30-12:45h Combination of BIO101 with antisense oligonucleotide therapy in severe SMA-like mice. Cynthia Bézier, Parvin Nazari Hashemi, Steve Cottin, René Lafont, Stanislas Veillet, Frédéric Charbonnier, Pierre J. Dilda, Mathilde Latil, Olivier Biondi. Biophytis, Sorbonne Université & Université de Paris, Faculté des Sciences Fondamentales et Biomédicales, INSERM UMR-S 1124 & Sorbonne Université, Paris-Seine Biology Institute (BIOSIPE), CNRS.
12:45-13h General discussion and brainstorming.
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